The longevity and health-testing market has exploded, and the platforms in it are far less alike than their marketing suggests. Some run a single deep blood panel and hand you a clinician-reviewed report. Some are hormone-optimization clinics built around testosterone and peptides. Others are memberships that test you a few times a year and adjust your plan as you go. Picking the wrong one means paying for things you do not need, or missing the monitoring you do.
This guide compares five of the most notable options in 2026: OneTwenty, Geviti, Marek Health, Function Health, and Mito Health. We break down what each one costs, how often it tests you, what it actually does with the results, and who it is right for, so you can choose with clear eyes.

The Quick Verdict
OneTwenty vs Geviti vs Marek vs Function vs Mito: Comparison Chart
| Feature | OneTwenty | Geviti | Marek Health | Function Health | Mito Health |
|---|---|---|---|---|---|
| Pricing | $499 / year | From ~$67/mo (Lite, billed $400 / 6 mo) | ~$225/mo + labs separate | $365 / year | $399 / test |
| Model | Membership, continuous | Membership | Coaching + a la carte labs | Membership | One-time test |
| Lab panels / year | 4 (quarterly) | 2 | Labs every 8 to 12 weeks (separate) | 2 | 1 |
| Biomarkers | 78 baseline, 20 to 40 per follow-up | 100+ | 130+ per panel | 100+ per panel | 100+ |
| Wearable / device data | ✓ 500+ daily signals + scale + BP | — | — | Limited | — |
| AI & coaching | ✓ 24/7 AI Health Coach | Specialist results review | Dedicated health coach | Clinician notes + action plan | AI advisor + 1:1 consult |
| Custom supplements | ✓ Formulated & delivered | Recommendations | Recommendations + supplements | Recommendations | Recommendations |
| Prescriptions (TRT / GLP-1 / HRT) | ✓ Direct via licensed clinicians | ✓ On Plus Rx tier | ✓ Hormones, peptides, GLP-1 | No | No |
| At-home blood draw | Add-on | ✓ Major metros | Lab visit (Labcorp) | Lab visit (Quest) | Lab visit (Quest/BioReference) |
| Available in New York | ✓ All 50 states | ✓ (NY pricing varies) | No (not NY/NJ/RI) | ✓ All 50 states | ✓ (NY pricing varies) |
| HSA / FSA eligible | ✓ | ✓ | ✓ | ✓ | ✓ |
How Much Do These Platforms Cost?
These five do not price the same way, so comparing a single number is misleading. Mito Health is a one-time $399 test. Function Health is a $365 yearly membership that includes two panels. Geviti is a membership starting around $67 per month (billed $400 every six months for the Lite tier), rising to about $130 to $150 per month for tiers that add prescriptions. Marek Health charges roughly $225 per month for its coaching program, with lab panels billed separately, so real first-year spend often runs $2,500 or more. OneTwenty is $499 per year, with medications and supplements billed as needed.
The more useful question is not the sticker price but how often you are actually tested for it, because that determines whether you get a yearly snapshot or an ongoing picture of your health.
What Are These Platforms and How Do They Work?
A standard annual physical usually runs fewer than 20 markers, leaving out advanced cardiovascular risk markers like ApoB and Lipoprotein(a), full hormone and thyroid panels, inflammatory markers, and nutrient status. Every platform here tests those deeper markers. The differences come down to three things: how often they test you, whether they only test or also treat, and whether they fold in data from your wearables and daily life.
On one end, Mito Health and Function Health are testing-first platforms that give you a thorough panel and a plan. In the middle, Geviti adds a membership cadence and prescription access on higher tiers. Marek Health is a hormone-optimization specialist with the deepest diagnostics and a treatment menu to match. And OneTwenty sits at the far end, combining quarterly labs with continuous wearable data, supplements, prescriptions, and a plan that is actively re-tuned every quarter.
The 5 Platforms, Reviewed
OneTwenty Review
Most platforms here test you once or twice a year and hand you a report. OneTwenty is built on the opposite premise: your own data should drive your plan, and that plan should keep changing as your body does. It tests you every quarter, watches your wearables in between, and re-optimizes your protocol every 90 days based on what your numbers are actually doing. It is the only option in this comparison that combines deep testing with continuous monitoring and the ability to treat. It is currently in closed beta, accepting members in small batches, and is available in all 50 states.
- Quarterly blood panels: 78 targeted biomarkers at baseline, then 20 to 40 focused markers every quarter, four times a year instead of once or twice.
- 500+ daily signals: Your wearable, smart scale, and blood pressure monitor stream sleep, HRV, heart rate, and body composition into one dashboard, so the gaps between labs are not blind spots.
- 24/7 AI Health Coach: It knows your labs, your wearable trends, and your protocol, and answers questions any time.
- Custom supplement delivery: Formulated from your labs and shipped in labeled pouches, updated each quarter.
- Prescription access: When labs show clinical need, licensed clinicians can prescribe TRT, GLP-1s, HRT, and more.
- Quarterly re-optimization: Every 90 days your supplements, medications, and recommendations are adjusted to your latest data.
Strengths
- The only true continuous-optimization model here
- Quarterly testing plus daily wearable data
- Tests, supplements, and prescribes in one place
- Available in all 50 states, including New York
Trade-offs
- Closed beta, so you may wait for a batch
- Medications and supplements billed separately
- More than you need if you only want one panel
Marek Health Review
Founded in 2021, Marek Health is the specialist of this group, built around the idea that you cannot optimize what you do not measure. Its diagnostics go deeper than anyone here, with 130+ biomarkers per panel, and its treatment menu spans TRT, peptides, GLP-1s, and more, all guided by a dedicated health coach who reviews your data and adjusts your protocol every 8 to 12 weeks. The trade-off is cost and reach: lab panels are billed on top of the roughly $225 per month coaching fee, real first-year spend often exceeds $2,500, and Marek is not available in New York, New Jersey, or Rhode Island.
- Deepest diagnostics: 130+ biomarkers per panel, the broadest hormone and metabolic testing in this comparison.
- Broad treatment menu: TRT, peptides, GLP-1s, and other therapies through partnered licensed providers.
- Dedicated health coach: A 1:1 relationship that builds and refines your protocol around your data.
Strengths
- The most comprehensive hormone diagnostics here
- Wide treatment menu, including peptides
- Hands-on health-coach model
Trade-offs
- Highest real cost of the group
- Labs billed separately on top of coaching
- Not available in NY, NJ, or RI
Geviti Review
Geviti takes a membership approach to longevity care. Every tier includes its 100+ biomarker Longeviti Panel twice a year, and its standout feature is convenience: Geviti offers at-home blood draws in major metro areas, with a walk-in lab option elsewhere. Pricing runs from about $67 per month for the Lite tier (billed $400 every six months) up to roughly $150 per month for the Plus Rx tier, which adds prescription access. You also get a results-review video with a specialist and specialty add-ons such as the DUTCH hormone test. Pricing in New York, New Jersey, and Rhode Island may vary.
- At-home draws: A phlebotomist comes to you in major metros, which none of the others offer as a core feature.
- Two panels a year: Included on every membership tier, so you see trends, not just a snapshot.
- Prescription tier: The Plus Rx membership adds prescription access for hormones and more.
Strengths
- At-home blood draws in major metros
- Two panels per year on every tier
- Prescription option on higher tier
Trade-offs
- No wearable integration
- Higher tiers get pricey
- NY/NJ/RI pricing may differ
Function Health Review
Founded in 2022 by Mark Hyman, MD, Function Health is one of the best-known names in direct-to-consumer testing, and its strength is breadth at a fair price. The membership includes a comprehensive panel of 100+ biomarkers plus a follow-up panel about six months later, with clinician notes and a personalized action plan. In 2026 Function lowered its price to $365 per year, down from $499, which makes it a strong value for people who primarily want wide diagnostic coverage. Optional Galleri multi-cancer detection and MRI add-ons are available at extra cost.
- Broad panels: 100+ biomarkers per panel across heart, thyroid, liver, kidney, metabolic, hormone, and nutrient categories.
- Clinician notes and action plan: Every biomarker is explained, with a call for any urgent results.
- Screening add-ons: Optional cancer detection and MRI options.
Strengths
- Excellent breadth for early detection
- Strong value at $365/yr for two panels
- Optional cancer and MRI screening
Trade-offs
- Twice-a-year testing, not continuous
- No medication prescribing
- Limited wearable integration
Mito Health Review
Mito Health keeps it simple: one comprehensive $399 panel of 100+ biomarkers, an AI advisor, and a 1:1 consultation with a licensed clinician to walk through your results. Backed by well-known longevity researchers and built around personalized reference ranges adjusted for your background, it also generates a biological age estimate from your blood data. Draws are done at Quest or BioReference locations nationwide. It is a strong choice for a thorough one-time baseline, though ongoing tracking means buying additional tests, and pricing in New York, New Jersey, and Rhode Island may vary.
- 100+ biomarkers: A broad one-time panel covering heart, metabolic, hormone, and nutrient markers.
- AI plus clinician: An AI advisor for ongoing questions, plus a real 1:1 consult to review results.
- Biological age: A blood-derived biological age estimate, with personalized reference ranges.
Strengths
- Strong one-time value at $399
- AI analysis plus a real clinician consult
- Biological age and personalized ranges
Trade-offs
- One test, not ongoing monitoring
- No prescriptions or wearable integration
- NY/NJ/RI pricing may differ
Mito Health vs Geviti: Which Should You Choose?
These two are the closest match in this group, so it is worth isolating. Both test 100+ biomarkers and both include clinician interpretation. The difference is structure. Mito Health is a one-time $399 test with an AI advisor and a 1:1 consult, ideal for a thorough baseline. Geviti is a membership starting around $67 per month that includes two panels a year and, crucially, at-home blood draws in major metros.
Choose Mito if you want a single deep snapshot with strong interpretation and a biological-age readout. Choose Geviti if you want ongoing twice-yearly testing and the convenience of a draw at home. And if you want more frequent testing layered with wearable data and the ability to actually treat what the labs find, that is where OneTwenty goes further than either.
Is OneTwenty Worth It?
At $499 per year, OneTwenty is not the cheapest entry here, but it is the only one doing continuous optimization rather than periodic testing. For that price you get four lab panels a year, 500+ daily signals from your wearables, a 24/7 AI Health Coach, custom supplements formulated from your results, and prescription access through licensed clinicians, with your protocol adjusted every 90 days. Marek goes deeper on hormones but costs far more and is unavailable in New York. Function and Mito test thoroughly but cannot treat. Geviti adds convenience but tests half as often and skips wearables.
If you only want a single snapshot, a cheaper one-time test will do the job. If you want your health actively managed and adjusted as your body changes, OneTwenty is the only option here built for that, and it works in all 50 states.
Sign up hereHow to Choose the Best Health Platform
Six questions to ask before you subscribe
- Snapshot or system? Decide whether you want a one-time baseline or a plan that updates as your numbers change.
- How often will you test? Once a year shows a snapshot. Quarterly testing shows trends, which is where most of the insight is.
- Do you want treatment, or just data? Some platforms only tell you what is off. Others can prescribe and deliver what addresses it.
- What is the real cost? Look past the headline price to separate lab fees, prescriptions, and supplements, which can add up fast on some platforms.
- Is it available where you live? Confirm state availability and regional pricing. Marek, for example, is not available in NY, NJ, or RI.
- How will you get drawn? If a lab visit is a barrier, prioritize platforms with at-home draws.
Frequently Asked Questions
Which platform is best overall?
For continuous optimization, OneTwenty leads, because it tests quarterly, integrates daily wearable data, delivers custom supplements, prescribes medication when needed, and adjusts your protocol every 90 days. For hormone depth, Marek Health. For value, Function Health. For convenience, Geviti. For a one-time baseline, Mito Health.
Which is cheapest?
It depends on the model. Function Health is $365 per year for two panels, Mito Health is $399 for one test, and Geviti starts around $67 per month. Marek Health is the most expensive once labs are added, often $2,500 or more in year one. OneTwenty is $499 per year for quarterly testing plus monitoring.
Which platforms are available in New York?
OneTwenty and Function Health are available in all 50 states. Geviti and Mito Health are available but note that pricing in NY, NJ, and RI may vary. Marek Health is not available in New York, New Jersey, or Rhode Island.
Which platforms can prescribe medication?
OneTwenty, Marek Health, and Geviti (on its Plus Rx tier) can connect you with licensed clinicians for prescriptions such as TRT, GLP-1s, or HRT. Function Health and Mito Health are testing-only and do not prescribe.
How often should you test your biomarkers?
Once a year gives a snapshot, which is fine for general screening. Testing two to four times a year reveals trends and shows whether your changes are working. OneTwenty's quarterly cadence gives the most responsive picture.
Do I still need my regular doctor?
Yes. These platforms complement primary care, not replace it. Use the data to have a more informed conversation with your physician.
Final Verdict: Which Health Platform Is Best?
The right platform depends on what you want. For the deepest hormone work, Marek Health is unmatched, if you can afford it and live outside NY, NJ, and RI. For comprehensive screening at a fair price, Function Health is the value pick. For at-home convenience, Geviti. For a single thorough baseline, Mito Health.
But if you want a platform that does not just test you and hand you a report, one that monitors your biology continuously and adjusts your plan as your body changes, OneTwenty is the clear choice. Quarterly labs, 500+ daily signals from your wearables, an AI health coach, custom supplement delivery, and prescription access, all in one membership, re-optimized every 90 days, available in all 50 states. No other platform here combines testing, monitoring, and treatment this completely.
Want your health actively optimized, not just measured?
OneTwenty combines quarterly labs, daily wearable monitoring, a 24/7 AI Health Coach, custom supplements, and prescription access in one membership, with your protocol adjusted every 90 days. Closed beta is accepting members in small batches.
Sign up here



