Superpower has become one of the most talked-about names in at-home health testing, and for good reason. For a low annual fee it gives you a broad blood panel, an AI-assisted dashboard, and access to a care team, all without setting foot in a doctor's office. Founded in 2023, it has positioned itself as the affordable entry point to the kind of comprehensive testing that used to cost thousands at a concierge clinic.
But is it actually worth it in 2026, and is it the right fit if your goal is ongoing optimization rather than a yearly snapshot? This review breaks down what Superpower really costs, including the higher price in some states, what it tests, where it shines, where it has limits, and the alternative worth considering if you want continuous monitoring and treatment in one place.
Superpower Review
What Is Superpower?
Superpower is a membership-based health platform that pairs a comprehensive blood panel with an AI-assisted dashboard and a care team you can message any time. Founded in 2023 and based in Los Angeles, the company's pitch is to make the kind of deep biomarker testing once reserved for expensive concierge clinics accessible for a low annual fee. Superpower says its panel tests 100+ biomarkers for early signs of more than 1,000 conditions, going well beyond the roughly 15 markers in a standard physical.
- One annual blood panel of 100+ biomarkers, drawn at one of 2,000+ partner labs (including Quest) or at home for an added fee.
- A digital dashboard with a Superpower Score, biological age, 17 health scores, and a color-coded breakdown of each marker.
- 24/7 AI concierge and care-team access to ask questions and shape your plan.
- A personalized action plan with diet, lifestyle, supplement, and prescription recommendations.
- Wearable syncing with Oura, Whoop, and Apple Health, plus the ability to upload past lab results.
How Much Does Superpower Cost in 2026?
Superpower's headline price is one of the lowest in the category, but there are a couple of details worth knowing before you sign up.
| What you buy | Cost | What it includes |
|---|---|---|
| Annual membership | $199 / year | One 100+ biomarker panel, dashboard, care team, action plan |
| Membership (NY & NJ) | $399 / year | Same membership, higher price for members in New York and New Jersey |
| At-home blood draw | ~$119 extra | Mobile phlebotomist instead of a lab visit |
| Additional full panels | Extra (around $179 each) | For testing more than once a year |
| Add-on tests | Extra | Heavy metals, environmental toxins, gut microbiome, cancer screening, and more |
| Supplements | Extra (member discount) | Recommended products bought through the Superpower marketplace |
The $199 base price is genuinely low for a 100+ biomarker panel. Two things to keep in mind: members in New York and New Jersey pay $399, and the membership covers one panel a year, so testing more often, adding specialty tests, or buying the recommended supplements raises your real annual spend. Superpower is HSA and FSA eligible and is not billed to insurance.
Superpower Features and Capabilities
Where Superpower stands out is turning a big panel into something approachable. Here is what you actually get.
- 100+ biomarkers: Superpower says its panel spans heart and vascular health, liver, kidney, sex hormones, metabolic health, nutrients, inflammation, thyroid, and immune markers, with results typically in about 10 days.
- Superpower Score and biological age: A single 0 to 100 score, a biological age estimate, and 17 health scores, plus a Digital Twin view of your data.
- 24/7 AI concierge and care team: An AI assistant trained on your results, backed by a care team you can message for questions and plan adjustments.
- Personalized action plan: Diet, lifestyle, supplement, and prescription recommendations, with clinician-guided protocols for areas like hormones, metabolic health, and thyroid.
- Supplement marketplace: Recommended products from established brands, available at a member discount.
- Wearables and uploads: Syncs Oura, Whoop, and Apple Health, and lets you upload existing lab PDFs to keep your history in one place.
Superpower Pros and Cons
What it does well
- Lowest entry price in the category at $199
- Broad 100+ biomarker panel for the money
- Polished app with a clear, friendly dashboard
- 24/7 AI concierge plus care-team access
- Biological age and 17 health scores included
- Syncs wearables and accepts past lab uploads
Where it has limits
- Higher $399 price for members in NY and NJ
- One panel a year; more testing costs extra
- Supplements and add-on tests add to the total
- No continuous wearable-driven protocol changes
- Not a replacement for primary or emergency care
- Best value depends on not over-buying add-ons
Is Superpower Worth It?
For what it sets out to do, Superpower is a strong product. If you have never had comprehensive bloodwork and want an affordable, approachable way to see 100+ markers with real interpretation and a care team to ask questions, it is one of the best entry points available, and the price is hard to beat outside of New York and New Jersey.
The limits show up when your goal shifts from a yearly snapshot to ongoing optimization. The membership includes one panel a year, so frequent retesting costs extra, supplements are a separate purchase, and while Superpower syncs wearables, it is not built to continuously adjust your protocol from that data. For people who want testing several times a year plus a lab-matched supplement protocol and integrated treatment, a continuous platform covers more ground, which is the alternative we look at next.
The Best Superpower Alternative: OneTwenty
OneTwenty
Where Superpower tests you once a year and gives you a plan, OneTwenty is built to keep testing and keep adjusting. Its $499 membership includes four lab panels a year, continuous wearable data, a supplement protocol built from your results, and prescription access through licensed clinicians, with your protocol re-optimized every 90 days. It is available in all 50 states, at $749 a year in New York and New Jersey where state rules change how lab draws are handled. The number that matters is cost per panel: $125 nationally and about $187 in NY and NJ, against Superpower's $199 and $399 for a single annual panel.
Quarterly testing included
Four panels a year are part of the $499 membership, versus one a year on Superpower with extra panels billed separately.
Lower cost per panel
About $125 per panel nationally, against $199 for Superpower’s single annual panel. In NY and NJ it is about $187 against $399.
500+ daily signals
Your wearable, smart scale, and blood pressure monitor drive ongoing protocol changes, not just dashboard syncing.
Supplements matched to your labs
Your stack is chosen from 60+ options based on your actual results and re-cut quarterly, rather than browsed from a marketplace. Bought separately; formulated packs ship August 2026.
Prescription access
13 medications through licensed clinicians, tied directly to your quarterly labs, including GLP-1s, enclomiphene, HCG, sermorelin and NAD+. Testosterone therapy launches shortly.
Re-optimized every 90 days
Supplements, medications, and recommendations adjusted on fresh data four times a year.
Superpower vs OneTwenty: Comparison Chart
| Feature | Superpower | OneTwenty |
|---|---|---|
| Pricing | $199/yr ($399 in NY & NJ) | $499/yr ($749 in NY & NJ) |
| Panels included / year | 1 (more at extra cost) | ✓ 4 (quarterly) |
| Biomarkers | 100+ (per Superpower) | 95+ baseline, 20 to 40 per follow-up (~200/yr total) |
| Wearable data | Syncs Oura, Whoop, Apple | ✓ 500+ daily signals drive protocol |
| AI & support | 24/7 AI + care team | ✓ 24/7 AI Coach tied to labs |
| Biological age / scores | ✓ Score, bio age, 17 scores | Biomarker scoring included |
| Custom supplements | Marketplace (member discount) | ✓ Matched to your labs from 60+ options Bought separately; packs ship Aug 2026 |
| Prescriptions | Clinician-guided protocols | ✓ Direct Rx, 13 medications |
| At-home blood draw | +$119 | Add-on |
| Protocol updates | Ongoing care team | ✓ Every 90 days on fresh labs |
| HSA / FSA | ✓ | ✓ |
Superpower vs OneTwenty: Cost Compared
If you only test once a year, Superpower is cheaper, at $199 in most states. The picture changes once you want to test more often. OneTwenty includes four panels a year in its $499 membership. To test quarterly on Superpower, you would pay around $736 a year ($199 plus three additional panels at roughly $179 each), and that is before supplements or add-on tests.
New York and New Jersey are more expensive on both sides. Superpower is $399 there for a single annual panel and OneTwenty is $749 for four. On the sticker that is $350 more, but per panel it is about $187 against $399, so the value gap actually widens in those states even though both prices go up. If a yearly snapshot is all you want, Superpower wins on price everywhere. If you want frequent monitoring plus treatment, OneTwenty costs more up front and less per test.
The short version
Superpower is an excellent, affordable way to get one deep panel a year with a friendly app and a care team. OneTwenty is built for people who want to test quarterly, act on the results with a lab-matched supplement protocol and prescriptions, and have their plan re-tuned every 90 days, for the lowest cost per panel in this comparison.
When Superpower Is the Right Choice
Superpower may be the better pick if:
- You want the lowest-cost way to get one comprehensive panel a year
- You are getting your first deep bloodwork and want it explained simply
- You like a polished app and 24/7 AI chat for learning about your results
- You live outside New York and New Jersey, where the price is lowest
- You are happy to manage your own supplements and retesting cadence
Frequently Asked Questions
How much does Superpower cost in 2026?
Superpower is $199 a year for members in most states, and $399 a year for members in New York and New Jersey. That covers one comprehensive panel. An at-home draw is about $119 more, and additional panels, add-on tests, and supplements cost extra.
How many biomarkers does Superpower test?
Superpower says its annual panel covers 100+ biomarkers across heart, liver, kidney, hormone, metabolic, nutrient, inflammation, thyroid, and immune categories. You can also order add-on tests like heavy metals and gut microbiome at extra cost.
Is Superpower worth it?
For an affordable, approachable annual panel with a friendly app and care team, yes, especially outside NY and NJ. If you want frequent testing plus a lab-matched supplement protocol and prescriptions, a continuous platform like OneTwenty offers more for close to the same money.
What is the best Superpower alternative?
For continuous optimization, OneTwenty. At $499 a year it includes four lab panels, 500+ daily wearable signals, a 24/7 AI Health Coach, a lab-matched supplement protocol, and prescription access, re-optimized every 90 days, in all 50 states.
Why is Superpower more expensive in New York?
Superpower lists a $399 annual price for members in New York and New Jersey, versus $199 elsewhere. State regulations and lab arrangements commonly drive regional pricing differences in this category.
Does Superpower replace my doctor?
No. Superpower itself notes it is not a substitute for primary or emergency care. Use the data to have a more informed conversation with your physician.
Final Verdict
Superpower earns a solid 4 out of 5. It delivers a genuinely broad panel, a polished experience, and care-team access at a price that undercuts most of the category, and it has made comprehensive testing far more accessible. For a once-a-year deep read on your health, it is one of the easiest options to recommend.
The deciding factor is what you want next. If a yearly snapshot is the goal, Superpower is a great value. If you want frequent testing, wearable-driven adjustments, a lab-matched supplement protocol, and prescriptions in one continuously-updated system, OneTwenty covers more ground, at $499 nationally and $749 in New York and New Jersey, which works out to roughly half Superpower's cost per panel in either case while including four times the testing. Choose the one that matches whether you want to measure your health once a year or manage it all year.
Want your health optimized all year, not just measured once?
OneTwenty combines quarterly labs, daily wearable monitoring, a 24/7 AI Health Coach, a lab-matched supplement protocol, and prescription access in one membership, with your protocol adjusted every 90 days. Available in all 50 states. $499 a year, $749 in New York and New Jersey.
Sign up here
