Quick reference
- When to use
- Use F32.3 when the client meets criteria for Major Depressive Disorder, Single Episode, Severe with Psychotic Features. Confirm episode type (single vs. recurrent) and severity level before coding. Always screen for bipolar history before assigning a unipolar depression code.
- Duration
- Symptoms must be present for at least 2 weeks. For recurrent codes (F33.x), document history of prior episodes with periods of remission. Reassess severity each session using PHQ-9.
- Session codes
- Pair with CPT 90791 (intake), 90834 (45-min), or 90837 (60-min). Use 96127 for PHQ-9 screening. Add 90863 for pharmacological management with therapy. Crisis sessions: 90839 + 90840.
- Key indicators
- Depressed mood or loss of interest/pleasure (at least one required) • Sleep changes • Appetite/weight changes • Fatigue • Worthlessness or guilt • Concentration difficulty • Psychomotor changes • Suicidal ideation
What F32.3 represents
Psychotic depression involves a major depressive episode accompanied by delusions, hallucinations, or both. This is a severe form of depression that often requires hospitalization and combined pharmacotherapy.
Key diagnostic criteria
- Meets criteria for severe MDD
- Psychotic features present: delusions and/or hallucinations
- Specify mood-congruent or mood-incongruent
- First depressive episode
Documentation essentials
Document both depressive and psychotic symptoms. Specify mood-congruence. Assess safety thoroughly.
Differential diagnosis
Critical to distinguish from schizoaffective disorder, schizophrenia, bipolar with psychosis, and delusional disorder.
Treatment planning
Combined antidepressant + antipsychotic. May require hospitalization. ECT may be considered for treatment-resistant cases.
Insurance & billing
Supports intensive treatment and potentially inpatient care.
Updates & changes
Monitor for clarifications on mood-congruent vs. incongruent specifiers.
Documentation pitfalls
Always specify mood-congruence. Don't miss this diagnosis – psychotic features change treatment approach significantly.
References
- American Psychiatric Association. (2022). Diagnostic and Statistical Manual of Mental Disorders (5th ed., text rev.).

